Final Publication

The code and key intermediate files in this repository correspond to the following manuscript:

Nearing, Douglas et al. Nature Comm. Microbiome differential abundance methods produce different results across 38 datasets.

Our goal with this work was to compare how similarly common DA methods perform on a range of 16S rRNA gene datasets. Accordingly for the majority of this work we don't necessarily know the right answer: we can mainly just say which tools are more similar to others. However, we also included several analyses to help gauge the false positive rate and consistency of the tools on different datasets from the same environment.

Final Publication Release

This release represents all code and data that has been used in the creation of the following publication:

Nearing, Douglas et al. _Nature Comm. Microbiome differential abundance methods produce different results across 38 datasets.