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Minimap2-2.28 (r1209)

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@lh3 lh3 released this 27 Mar 14:59
· 12 commits to master since this release

Notable changes to minimap2:

  • Bugfix: --MD was not working properly due to the addition of --ds in the
    last release (#1181 and #1182).

  • New feature: added an experimental preset lr:hqae for aligning accurate
    long reads back to their assembly. It has been observed that map-hifi and
    lr:hq may produce many wrong alignments around centromeres when accurate
    long reads (PacBio HiFi or Nanopore duplex/Q20+) are mapped to a diploid
    assembly constructed from them. This new preset produces much more accurate
    alignment. It is still experimental and may be subjective to changes in
    future.

  • Change: reduced the default --cap-kalloc to 500m to lower the peak
    memory consumption (#855).

Notable changes to mappy:

  • Bugfix: mappy option struct was out of sync with minimap2 (#1177).

Minimap2 should output identical alignments to v2.27.

(2.28: 27 March 2024, r1209)